Mistral Large 2411 123B has 122.6B parameters. In BF16 its weights alone take 228 GiB; quantized to 4-bit, about 69.0 GiB. Each 32K-token request adds 11.0 GiB of KV cache. Cheapest way to run it today: 6 × RTX A4000 (16 GB) at $0.432 per hour.
Read every day from Hugging Face. Split files are added together; vision projectors are left out.
How many GPUs to run Mistral Large 2411 123B
Fewest GPUs that fit the weights plus one 8K-token request. Data-center GPUs use vLLM (90% of memory usable), the others llama.cpp. Several GPUs split the model with tensor or pipeline parallelism.
GPU
BF16 / FP16
8-bit
4-bit
GeForce RTX 4090 24 GB
16 (several machines)
6
4
GeForce RTX 5090 32 GB
8
4
3
RTX PRO 6000 Blackwell 96 GB
3
2
1
Mac M5 Max 128 GB 96 GB usable
3
2
1
Ryzen AI Max+ 395 128 GB 96 GB usable
3
2
1
DGX Spark (GB10) 128 GB
2
1
1
NVIDIA H100 80 GB
4
2
2
NVIDIA H200 141 GB
2
1
1
NVIDIA B200 (HGX) 180 GB
2
1
1
8-bit: FP8 with vLLM (INT8 on GPUs without FP8), Q8_0 with llama.cpp. 4-bit: AWQ / GPTQ with vLLM, Q4_K_M with llama.cpp, both counted at the Q4_K_M size.
Cheapest way to run Mistral Large 2411 123B today
For each GPU: the fewest cards that fit Mistral Large 2411 123B with one 8K-token request, the most faithful weight format at that count, and the cheapest on-demand price (2026-10-30).
On-demand prices from AWS, Google Cloud, Azure, RunPod, Vast.ai, Oracle Cloud, OVHcloud, Scaleway, Verda, Akash and UpCloud, checked every hour. Serving many users needs more KV cache, so more memory: size it in the calculator. Some links are affiliate links: StudioTV may earn a commission, at no extra cost to you.
Architecture: 88 layers · GQA, 8 KV heads × 128. Every layer keeps keys and values for every token (grouped-query attention), so the cache grows linearly with context.
Context per request
BF16 cache
FP8 cache
8K tokens
2.75 GiB
1.38 GiB
32K tokens
11.0 GiB
5.50 GiB
128K tokens
44.0 GiB
22.0 GiB
Mistral Large 2411 123B VRAM FAQ
How much VRAM does Mistral Large 2411 123B need?
In BF16 the weights alone take 228 GiB (245 GB). In FP8 that is 115 GiB, and about 69.0 GiB with 4-bit quantization (Q4_K_M). Each request then adds KV cache: 2.75 GiB at 8K tokens and 11.0 GiB at 32K (BF16 cache).
Can Mistral Large 2411 123B run on a single RTX 4090 (24 GB)?
No. Even in 4-bit it needs 4 RTX 4090s. In 4-bit it fits on a single RTX PRO 6000 Blackwell (96 GB).
Can Mistral Large 2411 123B run on an RTX 5090 (32 GB)?
No. Even in 4-bit it needs 3 RTX 5090s.
Can Mistral Large 2411 123B run on a Mac?
Yes. In 4-bit (Q4_K_M with llama.cpp) it needs a Mac with 128 GB of unified memory or more, of which macOS gives the GPU about 96 GB, for one request with an 8K-token context. In 8-bit (Q8_0) it needs 192 GB or more.
Can Mistral Large 2411 123B run on a DGX Spark or a Ryzen AI Max+ 395 (128 GB)?
Yes. On a DGX Spark (128 GB) it fits in Q8_0 (118 GiB with an 8K-token context); on a Ryzen AI Max+ 395 with 128 GB, whose GPU gets up to 96 GB, it fits in Q4_K_M (71.8 GiB with an 8K-token context), with llama.cpp and one request.
What is the cheapest way to run Mistral Large 2411 123B?
On 2026-10-30, the cheapest on-demand setup is 6 × RTX A4000 (16 GB) with Q4_K_M weights on Vast.ai, at $0.432 per hour (about $315.36 per month). Next: 4 × GeForce RTX 3090 (24 GB) with Q4_K_M weights on Vast.ai, at $0.484 per hour. Sized for one 8K-token request; prices are checked every hour.
How many H100 GPUs does Mistral Large 2411 123B need?
With one request and an 8K-token context: 4 in BF16, 2 in FP8 and 2 in 4-bit (vLLM, 90% of memory usable). Serving many users at once needs more memory for their KV caches: the calculator sizes that for you.
Mistral Large 2411 123B VRAM badge
For a model card or a README: the 4-bit size and the smallest GPU it fits on, linked to this page. Data as JSON: /api/models/mistral-large-2411.json.
[](https://studiotvai.com/vram-requirements/mistral-large-2411)
Estimates, not guarantees: computed from the official config.json with the same engine as the LLM VRAM Calculator. Real usage depends on your engine version and settings.